蒋成飞，教授，博士，博士生导师

科学研究方向

RNA代谢调控与转化应用

联系方式

通讯：江苏省南京市江宁区龙眠大道101号病理学系，邮编211166

电邮：chengfeijiang@hotmail.com; chengfeijiang@njmu.edu.cn

简介

蒋成飞，教授、博士生导师，国家高层次青年人才，南京医科大学高层次引进人才及独立学术带头人。长期从事RNA代谢调控机制及其在临床转化中的研究。主要研究方向聚焦于：1. 系统解析RNA在生理与病理状态下的代谢全景图谱；2. RNA代谢调控因子的作用机制及其临床转化应用研究。近年来，以第一作者（含共一）身份在Gastroenterology、Journal of Hepatology、Journal of Clinical Investigation、Advanced Science、Cancer Letters及Molecular Cancer等国际知名期刊发表SCI论文十余篇，相关研究成果获 Journal of Hepatology和Gastroenterology等期刊的专题亮点评述。曾获美国国立卫生研究院（NIH）K22/R00项目资助（总经费约75万美元），并获得NIH杰出博士后研究奖。（本课题组常年招收博士后，欢迎联系）

承担科研课题

1.优秀青年科学基金项目（海外），肝脏RNA代谢调控与应用，在研，主持

代表性论文

1. Chengfei Jiang#, Zhe Li#,Sunmi Seok, Ping Li, Yonghe Ma, Stephanie K. Podguski, Shria Moturi, Nao Yoneda, Kenji Kawai, Shotaro Uehara, Yasuyuki Ohnishi, Hiroshi Suemizu, Jinwei Zhang, and Haiming Cao*. Systemic identification of functionally conserved lncRNA metabolic regulators between humans and mice. Gastroenterology， 2025 Mar 22:S0016-5085(25)00536-0. IF=26.3/一区

2. Chengfei Jiang, Ping Li, Yonghe Ma, Nao Yoneda, Kenji Kawai, Shotaro Uehara, Yasuyuki Ohnishi, Hiroshi Suemizu, Haiming Cao*. Comprehensive gene profiling of the metabolic landscape of humanized livers in mice. Journal of Hepatology. 2024 Apr;80(4):622-633. IF= 33 /一区（独立一作）

3.Chengfei Jiang, Ping Li, Haiming Cao*. Unveiling Tissue-Specific RNA Landscapes in Mouse Organs During Fasting and Feeding Using Nanopore Direct RNA Sequencing. Advanced Science. 2025 Feb;12(5):e2408054. IF=14.3/一区（独立一作）

4. Chengfei Jiang#, Yingchen Qian#, Xiaoming Bai#, Yunxia Xie, Shuangya Li, Yifan Lu, Zhimin Lu, Bingjie Liu, Bing-Hua Jiang*. The miR-152/SLC7A5/E2F1/PTBP1 axis mediates progression and therapy effect of triple-negative breast cancer through the crosstalk between amino acid metabolism and glycolysis pathway.Cancer Letters. 2025 May 1:617:217612. IF=10.1/一区

5.Zhe Li#, Sunmi Seok#, Chengfei Jiang#, Ping Li, Hang Sun, Haiming Cao*. Identification of GULF, a functionally conserved human lncRNA motif as a potential glucose and lipid-lowering therapeutic. Journal of Clinical Investigation，2025 Sep 16;135(18):e186355.，IF=13.3/一区

6.Xiangbo Ruan#, Ping Li#, Yonghe Ma#, Chengfei Jiang#, Yi Chen, Yu Shi, Nikhil Gupta, Fayaz Seifuddin, Mehdi Pirooznia, Yasuyuki Ohnishi, Nao Yoneda, Megumi Nishiwaki, Gabrijela Dumbovic, John L. Rinn, Yuichiro Higuchi, Kenji Kawai, Hiroshi Suemizu, Haiming Cao*, Identification of human long noncoding RNAs associated with nonalcoholic fatty liver disease and metabolic homeostasis, Journal of Clinical Investigation, 2021, 131(1). IF=19.5/一区

7. Chengfei Jiang#, Zhumei Shi#, Dongmei Li#, Yingchen Qian, Yi Ren, Xiaoming Bai, Yunxia Xie, Lin Wang, Xin Ge, Weitao Liu, Linlin Zhen, Lingzhi Liu, Binghua Jiang*. Estrogen-induced miR-196a elevation promotes tumor growth and metastasis via targeting SPRED1 in breast cancer, Molecular Cancer, 2018, 17(1): 83. IF=10.7/一区

(#共同第一作者)

获奖

NIH Fellows Award for Research Excellence，（NIH 2025年度杰出博后研究奖），2025